［Key words］ respiratory tract infections; immunity,cellular; aged
To collect information of the cellular immunity of aged patients with lower respiratory infection, and so as to provide reference for reasonable and effective intervention of the disease. Methods: The contents of lymphocytes CD3, CD4, CD8, CD4/CD8, CD16, CD19 in peripheral blood of aged patients with lower respiratory tract infection (group LRI) and healthy old people (group HOP) were detected with flow cytometry. Results: The levels of CD3, CD4, and CD4/CD8 in the group HOP were lower than those of young control group (YCG). The levels of CD3, CD4, CD4/CD8, and CD19 in group LRI were lower than those of groups YCG and HOP. The level of CD8 was higher in group LRI than that in YCG. The difference was significant(P<0.05). Conclusions: The occurrence and the progress of lower respiratory tract infection in aged people are related to disorder of cellular immunity. Monitoring on the changes of immunological function is helpful to the evaluation of individual immunity condition of aged people, and can provide reference to the prevention, treatment and effective intervention of the disease.
