[Key words] lymphoma,non-Hodgkin; lymph nodes; immunohistochemistry
To investigate the pathological and immunological features of lymph nodes of non-Hodgkin’s lymphoma outside lymph nodes in Guizhou province. Methods: Tissues of 180 cases of malignant lymphoma collected before were sliced and immunohistochemistry methods were adopted to analyze the specimens with markers of CD20, LCA, CD45RO, CD3, and CD56. Results: Among the 180 cases of malignant lymphoma, 66 cases were non-Hodgkin’s lymphoma outside lymph nodes (36.67%), of which 35 belonged to BCL (53.05%), 17 to TCL (10.61%), and 24 to NK/T (36.36%) according to the lymphoma tumor immunological classification. In regard to the lesion locations, 43 cases (65.15%) were mucosa-associated lymphoid tissue (MALT) lymphoma, and 20 cases (30.30%) located in other parts. Only three cases (4.55%) were skin associated lymphoid tissue (SALT) lymphoma. In regard to the histological classification, the top 3 types were nose tumor(23 cases, 34.8%),gastrointestinal.tumor(17 cass,25.76%),and suffusion Large-cell lymphoma(12 cases,18.18%).Conclusions: The pathological and immunological features of non-Hodgkin’s lymphoma in Guizhou are consistent with those of the state, except that the cases of type BCL are somewhat more than those of types TCL and NK/T.