［Key words］ hepatitis B virus; hepatitis B e antigens; polymerase chain reaction
To analyze the relationship between modes of serological HBV makers (HBVM) and HBV DNA levels in HBV-infected people. Methods: HBVM and HBV DNA of 542 HBV-infected persons were assayed by using time resolution fluorescence immunological analysis (TRFIA) and fluorescence quantitative PCR (FQ-PCR) techniques. Results: The general HBV DNA positive rate was 83.29%. Ten modes of HBVM were found among the 542 HBV-infected persons, and the positive rates of HBV DNA were significantly different among different modes of HBVM. Higher copy levels of serum HBV DNA occurred mainly in patients with HBeAg positive mode, and were significantly different from those of patients with other modes (P�0.05). Conclusions: The dynamic monitoring on contents of HBVM and HBV DNA could provide objective references and is helpful to the diagnosis and treatment of hepatitis B patients.
